Thursday, October 16, 2014

Could a chemical in broccoli, sprouts help treat autism?

A chemical found in broccoli and other vegetables - sulforaphane - has shown promise for improving some behavioral symptoms of autism. This is according to the results of a small clinical trial led by researchers from Johns Hopkins University School of Medicine in Baltimore, MD, and Massachusetts General Hospital for Children.
Broccoli
Researchers found that sulforaphane - a chemical found in broccoli and other vegetables - improved behavioral symptoms in some individuals with autism.
The team's findings are published in the Proceedings of the National Academy of Sciences (PNAS).
Autism is a developmental disability characterized by problems with social, emotional and communication skills, as well as repetitive and routine behaviors. Onset usually occurs before the age of 3 years, and the disorder is almost five times more common among boys than girls.
According to the Centers for Disease Control and Prevention (CDC), autism is the fastest growing disability in the US, with prevalence of the disorder increasing 289.5% over the past 12 years. More than 3.5 million Americans are living with autism.
At present, there are no medications that can treat the core symptoms of autism. But in this latest study, researchers found that sulforaphane could reduce certain behavioral symptoms of the disorder by targeting underlying cellular problems.

Wednesday, August 27, 2014

Children with autism 'have too many synapses in their brain'



A New study by researchers from the Columbia University Medical Center in New York, NY, finds that children and adolescents with autism have too many synapses in their brain, which can affect their brain function. Furthermore, the team believes it may be possible to reduce this excess synapse formation with a drug, paving the way for a novel autism treatment strategy.

autism synapses
Researchers found higher synapse formation in the brains of children with autism (right) than the brains of children without autism (left).
Image credit: Guomei Tang, Mark S. Sonders, CUMC
Around 1 in 68 children in the US have autism - a developmental condition characterized by behavioral, social and communication problems.
Exactly what causes autism is unclear, but researchers believe that it is triggered by abnormalities in the structure of the brain that stop it from functioning properly.
In this latest study, published in the journal Neuron, co-author Guomei Tang, PhD, assistant professor of neurology at Columbia University Medical Center (CUMC), analyzed 26 brains of children and adolescents with autism who had died from other causes, alongside 22 brains of children without autism.
Of the brains from those with autism, 13 came from children aged 2-9 years, while the remaining 13 came from teenagers aged 13-20 years.
Dr. Tang then assessed synapse density in each of the brains by counting how many tiny "spines" extended from them. The researchers note that synapses are where brain cells connect and communicate with each other. Each of the spines connects with a brain cell through a synapse....read more

SEE ALSO the video

Friday, June 20, 2014

Autism symptoms 'reversed' in mice by 100-year-old drug

An interesting finding reveals that a century-old drug, suramin , for African sleeping sickness has been used in a new study to reverse symptoms of autism in a mouse model.

 However, the biological and behavioral benefits of suramin were not permanent, nor preventive. A single dose remained effective in the mice for about five weeks, and then washed out. Moreover, suramin cannot be taken long-term since it can result in anemia and adrenal gland dysfunction. Still, Naviaux said these and earlier findings are sufficiently encouraging to soon launch a small phase 1 clinical trial with children who have ASD. He expects the trial to begin later this year. "Obviously correcting abnormalities in a mouse is a long way from a cure in humans, but we think this approach - antipurinergic therapy - is a new and fresh way to think about and address the challenge of autism. read more

Saturday, April 5, 2014

The Intense World Theory: The boy whose brain could unlock autism

Autism changed Henry Markram’s family. Now his Intense World theory could transform our understanding of the condition.

SOMETHING WAS WRONG with Kai Markram. At five days old, he seemed like an unusually alert baby, picking his head up and looking around long before his sisters had done. By the time he could walk, he was always in motion and required constant attention just to ensure his safety.
“He was super active, batteries running nonstop,” says his sister, Kali. And it wasn’t just boyish energy: When his parents tried to set limits, there were tantrums—not just the usual kicking and screaming, but biting and spitting, with a disproportionate and uncontrollable ferocity; and not just at age two, but at three, four, five and beyond. Kai was also socially odd : Sometimes he was withdrawn, but at other times he would dash up to strangers and hug them...... more

Friday, March 14, 2014

Causal link indicated between vitamin D, serotonin synthesis and autism

A new study by Rhonda Patrick, PhD and Bruce Ames, PhD of Children's Hospital Oakland Research Institute (CHORI) demonstrates the impact that Vitamin D may have on social behavior associated with Autism Spectrum Disorder (ASD). Dr. Patrick and Dr. Ames show that serotonin, oxytocin, and vasopressin, three brain hormones that affect social behavior, are all activated by vitamin D hormone. Autism, which is characterized by abnormal social behavior, has previously been linked to low levels of serotonin in the brain and to low vitamin D levels, but no mechanism has linked the two until now..........
Causal link indicated between vitamin D, serotonin synthesis and autism.

Tuesday, June 18, 2013

NEW RELEASE!!!!!!, AUTISM READ & WRITE

FINALLY!!!!, Autism Read & Write have been released to Google Play.

This new application, that we have created, is intended to help Autism Spectrum Disorder (ASD) children the basics of reading and writing.

Go to GooglePlay test it  and give us your opinion.


Monday, April 22, 2013

Propranolol Could Improve Working Memory In Autism


People with an Autism Spectrum Disorder (ASD) often have trouble communicating and interacting with others because they process language, facial expressions and social cues differently. Previously, researchers found that propranolol , a drug commonly used to treat high blood pressure, anxiety and panic, could improve the language abilities and social functioning of people with an ASD. Now, University of Missouri investigators say the prescription drug also could help improve the working memory abilities of individuals with autism ......

http://www.medicalnewstoday.com/releases/259176.php